‘Of course, that is about appropriate. I search for a Actual physical understanding of biological devices inside a bottom-up way. I feel you can distinguish 3 strains of research in my group at the moment. The initial problems chromosome structure: How can you have a metre-extensive DNA polymer folded and organised in such a microscopic mobile? Now we have developed visualisation strategies that make it possible for us to check how, as an example, SMC proteins loop DNA (video clip on Youtube) so as to Establish up chromosomes.

Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules

, Groningen scientists current the final results in their endeavours to help make labs more sustainable and supply guidelines for other labs. 

Nanofabrication of electrodes with sub-five nm spacing for transport experiments on one molecules and metal clusters

We establish place-of-care diagnostics check of neglected tropical diseases in just useful resource-minimal options, based on Crspr/Cas9 detecting of pathogen’s DNA in system fluids.

Within the years following these discoveries, my investigate pursuits shifted to biophysics and nanobiology, and I became less linked to the event of nanotube electronics. The focus of many scientists in the sector also shifted to graphene (in which, funnily sufficient, the first graphene ribbons were being referred to as ‘nanotubes which can be Reduce open up alongside their length’) just after the discovery of the two-dimensional substance in 2004.

MATLAB codes for knowledge processing are available at . Julia codes used for numerical simulation can be obtained at .

Atomic drive microscopy shows that vaccinia topoisomerase IB generates filaments on DNA within a cooperative vogue

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But carbon nanotubes have remained a investigation subject of considerable desire to a lot of. Certainly, the outlook on using carbon nanotubes to develop useful devices, in spots for example radio-frequency electronics, digital electronics and versatile electronics, remains dazzling.

FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial mobile division

2006, to start with demonstration of molecular sorting cees dekker within a lab on the chip utilizing biomotors; discovery of nanobubbles in stable-point out nanopores; and initial estimate of electrokinetic energy conversion in a nanofluidic channel

Visualization of unstained DNA nanostructures with advanced in-focus transmission electron microscopy techniques

Supercoiling-dependent DNA binding: quantitative modeling and applications to bulk and one-molecule experiments